First published: This round-up has been created from the Detailed Match Review posts. It will be updated 2 days before kick-off with any other important updates.
This Major League Soccer round-up brings together the key fixtures for Match Week 16 May 2026 to 22 May 2026, with a quick predictions table, predicted lineups, best odds and short match-by-match previews in one place.
Quick Predictions Table
| Match | Kick-off | Predicted score | Detailed Match Review |
|---|---|---|---|
| CF Montréal vs Chicago Fire | Sat 16 May 2026 21:30 BST | 2-1 | Read review |
| Philadelphia Union vs Columbus Crew | Sun 17 May 2026 00:30 BST | 2-1 | Read review |
| Orlando City vs Atlanta United | Sun 17 May 2026 00:30 BST | 2-1 | Read review |
| New York RB vs New York City | Sun 17 May 2026 00:30 BST | 2-1 | Read review |
| Charlotte vs Toronto | Sun 17 May 2026 00:30 BST | 1-0 | Read review |
| New England vs Minnesota United | Sun 17 May 2026 00:30 BST | 2-1 | Read review |
| DC United vs St. Louis City | Sun 17 May 2026 00:30 BST | 2-1 | Read review |
CF Montréal vs Chicago Fire
Kick-off: Sat 16 May 2026 21:30 BST
CF Montréal vs Chicago Fire Best Odds
Short form guide
The full-time probabilities keep CF Montréal vs Chicago Fire firmly in the competitive category, especially with the draw sitting at 25.76%. This is the type of match where control of territory and the first major chance could shape the rest of the afternoon. The score prediction is 2-1.
The Both Teams to Score number is one of the stronger signals in the preview, especially with Both Teams to Score: Yes 60.56%, No 39.44% and Total Goals Over/Under 2.5: Over 58.58%, Under 41.42%. If both teams commit players forward early, the game could become more open than the score prediction first suggests.
Recent results
CF Montréal last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 09/05/26 |  Montréal vs  Orlando City |
2 – 0 |
| Major League Soccer | 02/05/26 |  Atlanta United vs Montréal |
3 – 1 |
| Major League Soccer | 25/04/26 | Montréal vs  New York City |
1 – 0 |
Chicago Fire last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 09/05/26 |  Chicago Fire vs  New York RB |
1 – 3 |
| Major League Soccer | 03/05/26 | Chicago Fire vs  Cincinnati |
2 – 3 |
| Major League Soccer | 26/04/26 | Chicago Fire vs  Sporting KC |
5 – 0 |
Recent head-to-head
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 28/02/26 | Chicago Fire vs Montréal |
3 – 0 |
| Major League Soccer | 20/07/25 | Montréal vs Chicago Fire |
0 – 2 |
| Major League Soccer | 30/03/25 | Chicago Fire vs Montréal |
1 – 1 |
Predicted lineups
Key battles to watch
| CF Montréal | Chicago Fire | Key Battle Overview |
|---|---|---|
| CF Montréal | Chicago Fire | Iván Jaime will look to exploit the space in front of Andrew Gutman and give Montréal a direct route into the final third. |
| CF Montréal | Chicago Fire | Matty Longstaff against Anton Salétros could decide which side controls the midfield tempo and second balls. |
| CF Montréal | Chicago Fire | Iván Jaime is key for CF Montréal because his role in the attacking line gives them one of their clearest routes to creating chances. |
| CF Montréal | Chicago Fire | Hugo Cuypers is key for Chicago Fire because he is the main attacking outlet in their 4-2-3-1 and the player most likely to finish moves. |
Philadelphia Union vs Columbus Crew
Kick-off: Sun 17 May 2026 00:30 BST
Philadelphia Union vs Columbus Crew Best Odds
Short form guide
The full-time probabilities keep Philadelphia Union vs Columbus Crew firmly in the competitive category, especially with the draw sitting at 24.64%. This is the type of match where control of territory and the first major chance could shape the rest of the afternoon. The score prediction is 2-1.
The Both Teams to Score number is one of the stronger signals in the preview, especially with Both Teams to Score: Yes 56.44%, No 43.56% and Total Goals Over/Under 2.5: Over 53.68%, Under 46.32%. If both teams commit players forward early, the game could become more open than the score prediction first suggests.
Recent results
Philadelphia Union last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 09/05/26 |  New England vs  Philadelphia Union |
2 – 1 |
| Major League Soccer | 02/05/26 | Philadelphia Union vs  Nashville |
0 – 0 |
| Major League Soccer | 22/04/26 |  Toronto vs Philadelphia Union |
3 – 3 |
Columbus Crew last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 10/05/26 | New York City vs  Columbus Crew |
3 – 0 |
| Major League Soccer | 02/05/26 | Columbus Crew vs  Minnesota United |
2 – 3 |
| Major League Soccer | 23/04/26 | Columbus Crew vs  LA Galaxy |
2 – 1 |
Recent head-to-head
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 26/04/26 | Columbus Crew vs Philadelphia Union |
2 – 0 |
| Major League Soccer | 29/06/25 | Columbus Crew vs Philadelphia Union |
1 – 0 |
| Major League Soccer | 11/05/25 | Philadelphia Union vs Columbus Crew |
2 – 2 |
Predicted lineups
Key battles to watch
| Philadelphia Union | Columbus Crew | Key Battle Overview |
|---|---|---|
| Philadelphia Union | Columbus Crew | Ezekiel Alladoh against Andrés Herrera could be important because Philadelphia Union will want their forward to stretch the right side of the Columbus Crew defence. |
| Philadelphia Union | Columbus Crew | Cavan Sullivan against André Gomes is a key midfield duel because both sides will need control in central areas to build attacks. |
| Philadelphia Union | Columbus Crew | Ezekiel Alladoh is key for Philadelphia Union because he gives them a direct attacking option in a 4-4-2 and can help turn pressure into chances. |
| Philadelphia Union | Columbus Crew | Diego Rossi is key for Columbus Crew because he is one of their main attacking outlets and a central part of their recent goal threat. |
Orlando City vs Atlanta United
Kick-off: Sun 17 May 2026 00:30 BST
Orlando City vs Atlanta United Best Odds
Short form guide
The full-time probabilities keep Orlando City vs Atlanta United firmly in the competitive category, especially with the draw sitting at 24.09%. This is the type of match where control of territory and the first major chance could shape the rest of the afternoon. The score prediction is 2-1.
The Both Teams to Score number is one of the stronger signals in the preview, especially with Both Teams to Score: Yes 59.93%, No 40.07% and Total Goals Over/Under 2.5: Over 58.23%, Under 41.77%. If both teams commit players forward early, the game could become more open than the score prediction first suggests.
Recent results
Orlando City last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 09/05/26 | Montréal vs Orlando City |
2 – 0 |
| Major League Soccer | 02/05/26 |  Inter Miami vs Orlando City |
3 – 4 |
| Major League Soccer | 25/04/26 |  DC United vs Orlando City |
3 – 2 |
Atlanta United last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 09/05/26 | Atlanta United vs LA Galaxy |
1 – 2 |
| Major League Soccer | 02/05/26 | Atlanta United vs Montréal |
3 – 1 |
| Major League Soccer | 25/04/26 | Toronto vs Atlanta United |
1 – 2 |
Recent head-to-head
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 29/05/25 | Atlanta United vs Orlando City |
3 – 2 |
| Major League Soccer | 27/04/25 | Orlando City vs Atlanta United |
3 – 0 |
| Major League Soccer | 24/11/24 | Orlando City vs Atlanta United |
1 – 0 |
Predicted lineups
Key battles to watch
| Orlando City | Atlanta United | Key Battle Overview |
|---|---|---|
| Orlando City | Atlanta United | Justin Ellis against Elías Báez could be important because Orlando City will want Ellis to run at the left side of Atlanta United’s defence and test how well Báez handles direct pressure. |
| Orlando City | Atlanta United | Braian Ojeda against Aleksey Miranchuk looks like a key midfield duel, with Ojeda needing to disrupt Atlanta United’s main link player and stop him turning between the lines. |
| Orlando City | Atlanta United | Justin Ellis is key for Orlando City because he has been part of their recent attacking output and his movement can help turn their 5-3-2 into a threat on the break. |
| Orlando City | Atlanta United | Emmanuel Latte Lath is key for Atlanta United because he is the central attacking outlet in the predicted shape and gives them a direct route to goal. |
New York RB vs New York City
Kick-off: Sun 17 May 2026 00:30 BST
New York RB vs New York City Best Odds
Short form guide
New York RB vs New York City reads as one of the more finely balanced games in the round-up, with the draw percentage making a level match realistic. The prediction should therefore be viewed alongside the tactical setup rather than as a simple favourite-versus-outsider call. The score prediction is 2-1.
The probability split around goals keeps the match interesting from an attacking point of view: Both Teams to Score: Yes 60.65%, No 39.35% and Total Goals Over/Under 2.5: Over 58.35%, Under 41.65%. That makes the first goal important, because it could force the other side to take more risks.
Recent results
New York RB last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 09/05/26 | Chicago Fire vs New York RB |
1 – 3 |
| Major League Soccer | 02/05/26 | New York RB vs  Dallas |
0 – 2 |
| Major League Soccer | 25/04/26 | Cincinnati vs New York RB |
2 – 0 |
New York City last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 10/05/26 | New York City vs Columbus Crew |
3 – 0 |
| Major League Soccer | 03/05/26 | New York City vs DC United |
0 – 2 |
| Major League Soccer | 25/04/26 | Montréal vs New York City |
1 – 0 |
Recent head-to-head
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 28/09/25 | New York RB vs New York City |
2 – 3 |
| Major League Soccer | 17/05/25 | New York City vs New York RB |
2 – 0 |
| Major League Soccer | 23/11/24 | New York City vs New York RB |
0 – 2 |
Predicted lineups
Key battles to watch
| New York RB | New York City | Key Battle Overview |
|---|---|---|
| New York RB | New York City | Julian Hall against Nico Cavallo could be important if New York RB look to attack down that side and force New York City’s full-back into repeated defensive work. |
| New York RB | New York City | Adri Mehmeti against Agustín Ojeda is a useful midfield duel because both sides need control in central areas to set the tempo. |
| New York RB | New York City | Julian Hall is key for New York RB because he is the main attacking outlet in the predicted shape and the recent lineups show him starting up front. |
| New York RB | New York City | Nicolás Fernández Mercau is key for New York City because he is the listed attacker in the predicted 4-2-3-1 and the side’s main forward reference. |
Charlotte vs Toronto
Kick-off: Sun 17 May 2026 00:30 BST
Charlotte vs Toronto Best Odds
Short form guide
Charlotte vs Toronto carries a stronger statistical case for Charlotte, with the win probability giving them a clear advantage before kick-off. The underdog route is likely to depend on defensive control, set pieces and taking chances when the match opens up. The score prediction is 1-0.
The goals angle is more cautious than explosive, especially with Both Teams to Score: Yes 46.69%, No 53.31% and Total Goals Over/Under 2.5: Over 47.53%, Under 52.47%. A tight first half would fit that read and could make substitutions decisive later on.
Recent results
Charlotte last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 09/05/26 |  Charlotte vs Cincinnati |
2 – 2 |
| Major League Soccer | 02/05/26 | New England vs Charlotte |
1 – 0 |
| Major League Soccer | 26/04/26 | Nashville vs Charlotte |
4 – 2 |
Toronto last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 09/05/26 | Toronto vs Inter Miami |
2 – 4 |
| Major League Soccer | 02/05/26 | Toronto vs  SJ Earthquakes |
1 – 1 |
| Major League Soccer | 25/04/26 | Toronto vs Atlanta United |
1 – 2 |
Recent head-to-head
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 27/07/25 | Charlotte vs Toronto |
2 – 0 |
| Major League Soccer | 01/06/25 | Toronto vs Charlotte |
0 – 2 |
| Major League Soccer | 14/04/24 | Charlotte vs Toronto |
3 – 2 |
Predicted lineups
Key battles to watch
| Charlotte | Toronto | Key Battle Overview |
|---|---|---|
| Charlotte | Toronto | Idan Toklomati will look to use his movement against Kobe Franklin, with Charlotte likely trying to create space in the channels. |
| Charlotte | Toronto | Ashley Westwood against Alonso Coello is a key midfield duel because both sides need control in the centre of the pitch. |
| Charlotte | Toronto | Idan Toklomati is key for Charlotte because he is the central attacking outlet in the predicted shape and the main player to finish moves. |
| Charlotte | Toronto | Deandre Kerr is key for Toronto because he is the lone attacking reference in the predicted 4-2-3-1 and the main route to goal. |
New England vs Minnesota United
Kick-off: Sun 17 May 2026 00:30 BST
Short form guide
There is no huge separation between New England and Minnesota United in the result picture, and the draw probability underlines that. The forecast points towards a game where patience matters as much as attacking ambition. The score prediction is 2-1.
Chance creation at both ends is a major part of the match read, with Both Teams to Score: Yes 59.23%, No 40.77% and Total Goals Over/Under 2.5: Over 56.45%, Under 43.55%. The more aggressive side in transition may be the one that turns that goals angle into control.
Recent results
New England last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 09/05/26 | New England vs Philadelphia Union |
2 – 1 |
| Major League Soccer | 02/05/26 | New England vs Charlotte |
1 – 0 |
| Major League Soccer | 25/04/26 | Inter Miami vs New England |
1 – 1 |
Minnesota United last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 10/05/26 | Minnesota United vs  Austin |
2 – 2 |
| Major League Soccer | 02/05/26 | Columbus Crew vs Minnesota United |
2 – 3 |
| Major League Soccer | 25/04/26 | Minnesota United vs  Los Angeles |
0 – 1 |
Recent head-to-head
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 10/09/23 | Minnesota United vs New England |
1 – 1 |
| Major League Soccer | 19/06/22 | New England vs Minnesota United |
2 – 1 |
| Major League Soccer | 30/03/19 | New England vs Minnesota United |
2 – 1 |
Predicted lineups
Key battles to watch
| New England | Minnesota United | Key Battle Overview |
|---|---|---|
| New England | Minnesota United | Dor Turgeman against Jefferson Díaz could be decisive if New England’s forward can find space between the lines and turn chances into shots. |
| New England | Minnesota United | Alhassan Yusuf against Anthony Markanich Jr. looks important because control in midfield and the wide channels may shape who gets on the front foot. |
| New England | Minnesota United | Dor Turgeman is key for New England because he has been part of their recent attacking output and is named in the predicted front line again. |
| New England | Minnesota United | Joaquín Pereyra is key for Minnesota United because he is one of the main advanced outlets in their 3-4-2-1 and links their attacks. |
DC United vs St. Louis City
Kick-off: Sun 17 May 2026 00:30 BST
DC United vs St. Louis City Best Odds
Short form guide
DC United vs St. Louis City has a balanced result profile, with the draw probability at 26.74%. That makes the predicted scoreline important, because the numbers suggest a fixture where neither side is expected to run away with the match. The score prediction is 2-1.
The goal probabilities lean towards a more controlled match, with Both Teams to Score: Yes 53.16%, No 46.84% and Total Goals Over/Under 2.5: Over 49.23%, Under 50.73%. That makes patience, set pieces and defensive shape central to how the fixture may unfold.
Recent results
DC United last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 10/05/26 | Nashville vs DC United |
2 – 2 |
| Major League Soccer | 03/05/26 | New York City vs DC United |
0 – 2 |
| Major League Soccer | 25/04/26 | DC United vs Orlando City |
3 – 2 |
St. Louis City last three recorded results from the match preview:
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 10/05/26 |  Colorado Rapids vs  St. Louis City |
0 – 1 |
| Major League Soccer | 03/05/26 | Austin vs St. Louis City |
2 – 0 |
| Major League Soccer | 26/04/26 | St. Louis City vs SJ Earthquakes |
2 – 3 |
Recent head-to-head
| League | Date | Team | Score |
|---|---|---|---|
| Major League Soccer | 24/03/24 | St. Louis City vs DC United |
2 – 2 |
Predicted lineups
Key battles to watch
| DC United | St. Louis City | Key Battle Overview |
|---|---|---|
| DC United | St. Louis City | Jackson Hopkins against Dante Polvara is a key duel because Hopkins will look to attack the space behind the back line while Polvara has to hold his position and stop him turning. |
| DC United | St. Louis City | Brandon Servania against Conrad Wallem matters in midfield because both players will be central to controlling tempo and second balls. |
| DC United | St. Louis City | Jackson Hopkins is key for DC United because he has started in both of their recent lineups and gives them a direct attacking threat in the final third. |
| DC United | St. Louis City | Marcel Hartel is key for St. Louis City because he has featured in both recent 3-4-2-1 lineups and offers their main advanced creative presence. |
Best Odds
CF Montréal vs Chicago Fire
Latest bookmaker update: 2026-05-12 10:40:10
Philadelphia Union vs Columbus Crew
Latest bookmaker update: 2026-05-11 14:14:29
Orlando City vs Atlanta United
Latest bookmaker update: 2026-05-11 01:46:44
New York RB vs New York City
Latest bookmaker update: 2026-05-11 17:30:03
Charlotte vs Toronto
Latest bookmaker update: 2026-05-12 10:40:54
DC United vs St. Louis City
Latest bookmaker update: 2026-05-12 10:40:23
